The tissue
around the tumour
Mapping the extracellular matrix and immune neighbourhoods to understand cancer in its spatial context.
Spatial biologyBarts Cancer Institute · London
Understanding cancer.
In its context.
We explore how the architecture of tissues shapes cancer — bringing spatial biology, experimental models and AI into the same picture.
mAIques Lab
Queen Mary University of London
Our science
Different scales.
Connected questions.
From the organisation of collagen to the behaviour of a single cell, we ask how a tumour’s surroundings influence its next move.
The tissue
Biology
in three dimensions
Recreating tissue architecture to test how mechanics and collagen organisation influence invasion.
Experimental modelsA computational
view of cancer
Connecting tissue morphology with molecular features through machine learning and digital pathology.
AI & pathologySelected research · Nature Communications
How a tumour’s matrix can leave a lasting memory.
Our collaborative work explores how matrix mechano-sensing at the invasive front supports metastatic behaviour.
Read the studyThe structure of a tissue is part of its biology.
Our research perspectiveFrom the lab
New people. New questions.
New PhD projects in spatial biology and AI
Eve Guild and Bahar Sevgin join projects supported by Cancer Research UK and BBSRC.
Meet the teamSpringboard support for DERMIS
An Academy of Medical Sciences award supports our DERMIS project from 2026 to 2028.
Explore the awardExplore the lab
More ways to connect.
Research made possible by
Our funding
Good questions bring people together