AI & digital pathology
H&E-based MSI/MMR testing with AI in colorectal cancer: a multi-centred blinded evaluation
npj Digital Medicine · Published online December 2025
Our work in print
Ideas, experiments
and discoveries.
Selected research from the lab and Oscar’s wider collaborations.
Matrix & mechanobiology
Matrix mechano-sensing at the invasive front induces a cytoskeletal and transcriptional memory supporting metastasis
Nature Communications
Cancer cell biology
SLC7A11 protects amoeboid-disseminating cancer cells from oxidative stress
Cell Reports
AI & digital pathology
A systematic pan-cancer study on deep learning-based prediction of multi-omic biomarkers from routine pathology images
Communications Medicine
Cancer cell biology
LAP1 supports nuclear adaptability during constrained melanoma cell migration and invasion
Nature Cell Biology
Cancer cell biology
CD73 controls Myosin II–driven invasion, metastasis, and immunosuppression in amoeboid pancreatic cancer cells
Science Advances
Methods & reviews
Multiplex chromogenic immunohistochemistry to stain and analyze paraffin tissue sections from the mouse or human
STAR Protocols
Methods & reviews
The amoeboid state as part of the epithelial-to-mesenchymal transition programme
Trends in Cell Biology
Cancer cell biology
A preclinical pipeline to evaluate migrastatics as therapeutic agents in metastatic melanoma
British Journal of Cancer
Cancer cell biology
WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities and melanoma amoeboid invasion
Nature Communications
Cancer cell biology
Myosin II reactivation and cytoskeletal remodeling as a hallmark and a vulnerability in melanoma therapy resistance
Cancer Cell
Cancer cell biology
EGFR downregulation facilitates TGF-beta-induced amoeboid transition in hepatocellular carcinoma
Cancer Letters